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KMID : 0365220120490010013
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Korean Journal of Public Health
2012 Volume.49 No. 1 p.13 ~ p.20
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The impact of lifetime smoking on cognitive decline - Evidence from the Korean Longitudinal Study of Aging
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Min Jin-Young
Cho Sung-Il
Park Su-San
Min Kyoung-Bok
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Abstract
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Objectives: We investigated the relationship between lifetime smoking history (i.e., the age of smoking commencement, the duration of smoking, and the number of cigarettes smoked per day or year) and cognitive decline among male smokers aged middle and older, with a nationally representative sample from the Korean Longitudinal Study of Aging (KLoSA).
Method: Study population was 2,294 male smokers with complete smoking histories and who participated in the follow-up study between 2006 and 2008. All participants performed the Korean version of the Mental State Examination (K-MMSE) and responded to the questionnaire regarding smoking history, general characteristics, and chronic diseases. For the aim of the study, the calculation of least square means, general linear regression and general additive model were conducted.
Results: After adjusting for confounding variables, smokers who began smoking before age 20, had higher MMSE declines than those who initiated smoking after age 20 (-1.23 vs. -0.50, p=0.019). Total smoking of more than 40 pack-years was significantly associated with the greatest declines in MMSE.
Conclusion: Our findings suggest that an early onset of smoking (before the age of 20) and greater pack-years of smoking exposure increase the risk of MMSE declines.
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KEYWORD
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mental state examination, lifetime smoking, age of smoking commencement, pack-years of smoking
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